5TC5
Crystal structure of human 5'-deoxy-5'-methylthioadenosine phosphorylase in complex with butylthio-DADMe-Immucillin-A and chloride
Summary for 5TC5
Entry DOI | 10.2210/pdb5tc5/pdb |
Related | 1K27 3OZC 3OZD 3OZE 5TC6 5TC7 5TC8 |
Descriptor | S-methyl-5'-thioadenosine phosphorylase, (3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-[(butylsulfanyl)methyl]pyrrolidin-3-ol, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | phosphorylase, inhibitor, complex, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 3 |
Total formula weight | 100505.37 |
Authors | Cameron, S.A.,Firestone, R.S.,Schramm, V.L.,Almo, S.C. (deposition date: 2016-09-14, release date: 2017-10-11, Last modification date: 2023-10-04) |
Primary citation | Firestone, R.S.,Cameron, S.A.,Karp, J.M.,Arcus, V.L.,Schramm, V.L. TBA To be published, |
Experimental method | X-RAY DIFFRACTION (1.96 Å) |
Structure validation
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