5TC5
Crystal structure of human 5'-deoxy-5'-methylthioadenosine phosphorylase in complex with butylthio-DADMe-Immucillin-A and chloride
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C | S-methyl-5'-thioadenosine phosphorylase | polymer | 297 | 33119.1 | 3 | UniProt (Q13126) Pfam (PF01048) In PDB | Homo sapiens (Human) | 5'-methylthioadenosine phosphorylase,MTAPase |
2 | A, B, C | (3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-[(butylsulfanyl)methyl]pyrrolidin-3-ol | non-polymer | 335.5 | 3 | Chemie (BIG) | |||
3 | A, B, C | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
4 | water | water | 18.0 | 228 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 283 (UniProt: Q13126)
PDB | External Database | Details |
---|---|---|
Met -13 | - | initiating methionine |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
His -9 | - | expression tag |
His -8 | - | expression tag |
His -7 | - | expression tag |
Glu -6 | - | expression tag |
Asn -5 | - | expression tag |
Leu -4 | - | expression tag |
Tyr -3 | - | expression tag |
Phe -2 | - | expression tag |
Gln -1 | - | expression tag |
Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 99357.2 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 1148.2 | |
All* | Total formula weight | 100505.4 |