5T89

Crystal structure of VEGF-A in complex with VEGFR-1 domains D1-6

5T89 の概要

• エントリーDOI: 10.2210/pdb5t89/pdb
• 分子名称: Vascular endothelial growth factor A, Vascular endothelial growth factor receptor 1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• 機能のキーワード: receptor tyrosine kinase, growth factor, immunoglobulin domain, transferase
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 182190.52

構造登録者

Markovic-Mueller, S.,Stuttfeld, E.,Asthana, M.,Weinert, T.,Bliven, S.,Goldie, K.N.,Kisko, K.,Capitani, G.,Ballmer-Hofer, K. (登録日: 2016-09-07, 公開日: 2017-02-01, 最終更新日: 2020-07-29)

• 主引用文献: Markovic-Mueller, S.,Stuttfeld, E.,Asthana, M.,Weinert, T.,Bliven, S.,Goldie, K.N.,Kisko, K.,Capitani, G.,Ballmer-Hofer, K.; Structure of the Full-length VEGFR-1 Extracellular Domain in Complex with VEGF-A.; Structure, 25:341-352, 2017; PubMed: 28111021; DOI: 10.1016/j.str.2016.12.012

実験手法

X-RAY DIFFRACTION (4 Å)