5T7L
Pt(II)-mediated copper-dependent interactions between ATOX1 and MNK1
Summary for 5T7L
Entry DOI | 10.2210/pdb5t7l/pdb |
Descriptor | Copper transport protein ATOX1, Copper-transporting ATPase 1, PLATINUM (II) ION, ... (5 entities in total) |
Functional Keywords | atox1-mnk1, pt-binding, heterodimer, transport protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 16229.30 |
Authors | Caliandro, R.,Mirabelli, V.,Caliandro, R.,Rosato, A.,Lasorsa, A.,Galliani, A.,Arnesano, F.,Natile, G. (deposition date: 2016-09-05, release date: 2016-10-12, Last modification date: 2024-01-17) |
Primary citation | Lasorsa, A.,Nardella, M.I.,Rosato, A.,Mirabelli, V.,Caliandro, R.,Caliandro, R.,Natile, G.,Arnesano, F. Mechanistic and Structural Basis for Inhibition of Copper Trafficking by Platinum Anticancer Drugs. J.Am.Chem.Soc., 141:12109-12120, 2019 Cited by PubMed: 31283225DOI: 10.1021/jacs.9b05550 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.83 Å) |
Structure validation
Download full validation report