5SW3
Crystal Structure of TGT in complex with 3-Pyridinecarboxylic acid, 6-(dimethylamino)
Summary for 5SW3
| Entry DOI | 10.2210/pdb5sw3/pdb |
| Descriptor | Queuine tRNA-ribosyltransferase, ZINC ION, DIMETHYL SULFOXIDE, ... (7 entities in total) |
| Functional Keywords | tgt, trna, guanine exchange enzyme, protein interface, transferase |
| Biological source | Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) |
| Total number of polymer chains | 1 |
| Total formula weight | 42695.99 |
| Authors | Hassaan, E.,Heine, A.,Klebe, G. (deposition date: 2016-08-08, release date: 2017-07-19, Last modification date: 2024-01-17) |
| Primary citation | Hassaan, E.,Eriksson, P.O.,Geschwindner, S.,Heine, A.,Klebe, G. Fragments as Novel Starting Points for tRNA-Guanine Transglycosylase Inhibitors Found by Alternative Screening Strategies. Chemmedchem, 15:324-337, 2020 Cited by PubMed: 31808981DOI: 10.1002/cmdc.201900604 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.38 Å) |
Structure validation
Download full validation report
