5QIR

Covalent fragment group deposition -- Crystal Structure of OUTB2 in complex with PCM-0102305

Summary for 5QIR

• Entry DOI: 10.2210/pdb5qir/pdb
• Group deposition: Covalent fragment group deposition (G_1002053)
• Descriptor: Ubiquitin thioesterase OTUB2, N-[(4-fluoro-3-methylphenyl)methyl]acetamide, DI(HYDROXYETHYL)ETHER, ... (5 entities in total)
• Functional Keywords: sgc - diamond i04-1 fragment screening, xchemexplorer, protease otub2, deubiquitinating enzyme otub2, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 26959.67

Authors

Sethi, R.,Douangamath, A.,Resnick, E.,Bradley, A.R.,Collins, P.,Brandao-Neto, J.,Talon, R.,Krojer, T.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.,London, N.,von Delft, F. (deposition date: 2018-08-10, release date: 2019-12-18)

• Primary citation: Sethi, R.,Douangamath, A.,Resnick, E.,Bradley, A.R.,Collins, P.,Brandao-Neto, J.,Talon, R.,Krojer, T.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.,London, N.,von Delft, F.; Covalent fragment group deposition; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.43 Å)