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5PAY

Crystal Structure of Factor VIIa in complex with 1-[[3-[5-hydroxy-4-(1H-pyrrolo[3,2-c]pyridin-2-yl)pyrazol-1-yl]phenyl]methyl]-3-phenylurea

Summary for 5PAY
Entry DOI10.2210/pdb5pay/pdb
Group depositionCrystal Structures of Factor VIIa Complexes (G_1002015)
DescriptorCoagulation factor VII light chain, Coagulation factor VII heavy chain, SULFATE ION, ... (8 entities in total)
Functional Keywordsglycoprotein, hydrolase, serine protease, plasma, blood coagulation factor, protein inhibitor complex, calcium-binding, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHomo sapiens (Human)
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Cellular locationSecreted: P08709 P08709
Total number of polymer chains2
Total formula weight36092.01
Authors
Stihle, M.,Mayweg, A.,Roever, S.,Rudolph, M.G. (deposition date: 2016-11-10, release date: 2017-06-21, Last modification date: 2024-10-30)
Primary citationMayweg, A.,Roever, S.,Rudolph, M.G.
Crystal Structure of a Factor VIIa complex
To be published,
Experimental method
X-RAY DIFFRACTION (1.66 Å)
Structure validation

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