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5PAC

human factor VIIa in complex with 5-hydroxy-N-(4-oxo-3H-quinazolin-6-yl)-1-[3-[(phenylcarbamoylamino)methyl]phenyl]pyrazole-4-carboxamide at 1.50A

Summary for 5PAC
Entry DOI10.2210/pdb5pac/pdb
Group depositionCrystal Structures of Factor VIIa Complexes (G_1002015)
DescriptorCoagulation factor VII light chain, Coagulation factor VII heavy chain, GLYCEROL, ... (8 entities in total)
Functional Keywordsglycoprotein, hydrolase, serine protease, plasma, blood coagulation factor, protein inhibitor complex, calcium-binding, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHomo sapiens (Human)
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Cellular locationSecreted: P08709 P08709
Total number of polymer chains2
Total formula weight36035.50
Authors
Stihle, M.,Mayweg, A.,Roever, S.,Rudolph, M.G. (deposition date: 2016-11-10, release date: 2017-06-21, Last modification date: 2024-10-23)
Primary citationMayweg, A.,Roever, S.,Rudolph, M.G.
Crystal Structure of a Factor VIIa complex
To be published,
Experimental method
X-RAY DIFFRACTION (1.5 Å)
Structure validation

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