Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0004252 | molecular_function | serine-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 301 |
| Chain | Residue |
| A | LYS197 |
| A | ILE198 |
| A | LEU201 |
| A | GLU202 |
| B | TRP416 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 302 |
| Chain | Residue |
| A | HOH404 |
| A | HOH411 |
| A | HOH412 |
| A | HOH418 |
| A | ARG173 |
| A | CYS174 |
| A | SER179 |
| A | LEU180 |
| site_id | AC3 |
| Number of Residues | 21 |
| Details | binding site for residue 7Y7 B 501 |
| Chain | Residue |
| B | HIS253 |
| B | CYS254 |
| B | ASP256 |
| B | LYS257 |
| B | GLY297 |
| B | ASP398 |
| B | SER399 |
| B | CYS400 |
| B | LYS401 |
| B | SER404 |
| B | SER423 |
| B | TRP424 |
| B | GLY425 |
| B | GLN426 |
| B | GLY427 |
| B | CYS428 |
| B | HOH629 |
| B | HOH637 |
| B | HOH734 |
| B | HOH746 |
| B | HOH772 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue CA B 502 |
| Chain | Residue |
| B | GLU270 |
| B | ASP272 |
| B | GLU275 |
| B | GLU280 |
| B | HOH739 |
| B | HOH798 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue CL B 503 |
| Chain | Residue |
| B | ARG262 |
| B | VAL459 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 B 504 |
| Chain | Residue |
| B | MET366 |
| B | THR367 |
| B | ARG439 |
| B | HOH602 |
| B | HOH636 |
| B | HOH674 |
| B | HOH761 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 B 505 |
| Chain | Residue |
| A | HOH404 |
| B | SER453 |
| B | GLU454 |
| B | ARG456 |
| B | HOH660 |
| B | HOH758 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC |
| Chain | Residue | Details |
| B | VAL249-CYS254 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DSckGDSGGPHA |
| Chain | Residue | Details |
| B | ASP398-ALA409 | |
| site_id | PS01186 |
| Number of Residues | 16 |
| Details | EGF_2 EGF-like domain signature 2. CrCheGYslladgvsC |
| Chain | Residue | Details |
| A | CYS172-CYS187 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19167329","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"3264725","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Charge relay system","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
