5PAB

Crystal Structure of Factor VIIa in complex with 1-[[3-[2-hydroxy-3-(1H-pyrrolo[3,2-c]pyridin-2-yl)phenyl]phenyl]methyl]-3-phenylurea

5PAB の概要

• エントリーDOI: 10.2210/pdb5pab/pdb
• Group deposition: Crystal Structures of Factor VIIa Complexes (G_1002015)
• 分子名称: Coagulation factor VII heavy chain, Coagulation factor VII light chain, 1-[[3-[2-oxidanyl-3-(1~{H}-pyrrolo[3,2-c]pyridin-2-yl)phenyl]phenyl]methyl]-3-phenyl-urea, ... (8 entities in total)
• 機能のキーワード: glycoprotein, hydrolase, serine protease, plasma, blood coagulation factor, protein inhibitor complex, calcium-binding, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Secreted: P08709 P08709
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 36245.59

構造登録者

Stihle, M.,Mayweg, A.,Roever, S.,Rudolph, M.G. (登録日: 2016-11-10, 公開日: 2017-06-21, 最終更新日: 2024-11-13)

• 主引用文献: Mayweg, A.,Roever, S.,Rudolph, M.G.; Crystal Structure of a Factor VIIa complex; To be published,

実験手法

X-RAY DIFFRACTION (1.99 Å)