5OXS

Crystal structure of human lung surfactant protein D trimeric fragment with bound ligand Salmonella enterica Minnesota R5 oligosaccharide

Summary for 5OXS

• Entry DOI: 10.2210/pdb5oxs/pdb
• Related: 5OXR
• Descriptor: Pulmonary surfactant-associated protein D, alpha-D-glucopyranose-(1-3)-L-glycero-alpha-D-manno-heptopyranose-(1-3)-L-glycero-alpha-D-manno-heptopyranose-(1-5)-4,7-anhydro-3-deoxy-D-gluco-oct-2-ulosonic acid, CALCIUM ION, ... (4 entities in total)
• Functional Keywords: trimeric recombinant collectin fragment, neck+crd, alpha-helical coiled coil, carbohydrate recognition domain, lectin, sugar binding protein, surfactant protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 3
• Total formula weight: 59005.21

Authors

Shrive, A.K.,Greenhough, T.J. (deposition date: 2017-09-07, release date: 2018-06-20, Last modification date: 2024-01-17)

• Primary citation: Littlejohn, J.R.,da Silva, R.F.,Neale, W.A.,Smallcombe, C.C.,Clark, H.W.,Mackay, R.A.,Watson, A.S.,Madsen, J.,Hood, D.W.,Burns, I.,Greenhough, T.J.,Shrive, A.K.; Structural definition of hSP-D recognition of Salmonella enterica LPS inner core oligosaccharides reveals alternative binding modes for the same LPS.; PLoS ONE, 13:e0199175-e0199175, 2018; PubMed: 29912941; DOI: 10.1371/journal.pone.0199175

Experimental method

X-RAY DIFFRACTION (1.65 Å)