5OUS
Crystal Structure of the Protein-Kinase A catalytic subunit from Criteculus Griseus in complex with compounds RKp193
Summary for 5OUS
| Entry DOI | 10.2210/pdb5ous/pdb |
| Descriptor | cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (4 entities in total) |
| Functional Keywords | complex, peptidic ligand, transferase |
| Biological source | Cricetulus griseus (Chinese hamster) More |
| Total number of polymer chains | 2 |
| Total formula weight | 43257.08 |
| Authors | Mueller, J.M.,Heine, A.,Klebe, G. (deposition date: 2017-08-24, release date: 2018-09-05, Last modification date: 2019-05-15) |
| Primary citation | Mueller, J.M.,Kirschner, R.,Geyer, A.,Klebe, G. Conceptional Design of Self-Assembling Bisubstrate-like Inhibitors of Protein Kinase A Resulting in a Boronic Acid Glutamate Linkage Acs Omega, 2019 Cited by DOI: 10.1021/acsomega.8b02364PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.21 Å) |
Structure validation
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