5OTT

Extracellular domain of GLP-1 receptor in complex with exendin-4 variant Gly2Hcs/Thr5Hcs

5OTT の概要

• エントリーDOI: 10.2210/pdb5ott/pdb
• 分子名称: Glucagon-like peptide 1 receptor, Exendin-4 (3 entities in total)
• 機能のキーワード: glucagon-like peptide 1, gpcr, cyclic peptides, signaling protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 17815.66

構造登録者

Mortensen, S. (登録日: 2017-08-22, 公開日: 2018-07-04, 最終更新日: 2024-03-06)

• 主引用文献: Oddo, A.,Mortensen, S.,Thogersen, H.,De Maria, L.,Hennen, S.,McGuire, J.N.,Kofoed, J.,Linderoth, L.,Reedtz-Runge, S.; alpha-Helix or beta-Turn? An Investigation into N-Terminally Constrained Analogues of Glucagon-like Peptide 1 (GLP-1) and Exendin-4.; Biochemistry, 57:4148-4154, 2018; PubMed: 29877701; DOI: 10.1021/acs.biochem.8b00105

実験手法

X-RAY DIFFRACTION (1.92 Å)