5OSB

GLIC-GABAAR alpha1 chimera crystallized in complex with THDOC at pH4.5

5OSB の概要

• エントリーDOI: 10.2210/pdb5osb/pdb
• 分子名称: Proton-gated ion channel,Gamma-aminobutyric acid receptor subunit alpha-1,Gamma-aminobutyric acid receptor subunit alpha-1, Tetrahydrodeoxycorticosterone, ACETATE ION, ... (4 entities in total)
• 機能のキーワード: gabaa-receptor ion channel ion transport extracellular ligand gated ion channel, transport protein
• 由来する生物種: Gloeobacter violaceus (strain PCC 7421); 詳細
• 細胞内の位置: Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein: P62812
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 195259.49

構造登録者

Laverty, D.C.,Gold, M.G.,Smart, T.G. (登録日: 2017-08-17, 公開日: 2017-10-11, 最終更新日: 2024-01-17)

• 主引用文献: Laverty, D.,Thomas, P.,Field, M.,Andersen, O.J.,Gold, M.G.,Biggin, P.C.,Gielen, M.,Smart, T.G.; Crystal structures of a GABAA-receptor chimera reveal new endogenous neurosteroid-binding sites.; Nat. Struct. Mol. Biol., 24:977-985, 2017; PubMed: 28967882; DOI: 10.1038/nsmb.3477

実験手法

X-RAY DIFFRACTION (3.8 Å)