5OKP

Crystal structure of human SHIP2 Phosphatase-C2 double mutant F593D/L597D

Summary for 5OKP

• Entry DOI: 10.2210/pdb5okp/pdb
• Descriptor: Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2, 1,2-ETHANEDIOL (3 entities in total)
• Functional Keywords: ship2, phosphatase, c2, phosphatidylinositol (3, 4, 5)-triphosphate, hydrolase
• Biological source: Homo sapiens (Human)
• Cellular location: Cytoplasm, cytosol: O15357
• Total number of polymer chains: 1
• Total formula weight: 52968.62

Authors

Le Coq, J.,Lietha, D. (deposition date: 2017-07-25, release date: 2017-08-23)

• Primary citation: Le Coq, J.,Camacho-Artacho, M.,Velazquez, J.V.,Santiveri, C.M.,Gallego, L.H.,Campos-Olivas, R.,Dolker, N.,Lietha, D.; Structural basis for interdomain communication in SHIP2 providing high phosphatase activity.; Elife, 6:-, 2017; PubMed: 28792888; DOI: 10.7554/eLife.26640

Experimental method

X-RAY DIFFRACTION (1.85 Å)