5OKP
Crystal structure of human SHIP2 Phosphatase-C2 double mutant F593D/L597D
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 | polymer | 461 | 52720.3 | 1 | UniProt (O15357) | Homo sapiens (Human) | Inositol polyphosphate phosphatase-like protein 1,INPPL-1,Protein 51C,SH2 domain-containing inositol 5'-phosphatase 2,SHIP-2 |
| 2 | B, C, D, E (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 3 | F (A) | water | water | 18.0 | 139 | Chemie (HOH) |
Sequence modifications
A: 420 - 878 (UniProt: O15357)
| PDB | External Database | Details |
|---|---|---|
| Gly 418 | - | expression tag |
| Pro 419 | - | expression tag |
| Asp 593 | Phe 593 | engineered mutation |
| Asp 597 | Leu 597 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 52720.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 248.3 | |
| All* | Total formula weight | 52968.6 |
