5OHH

Crystal structure of human carbonic anhydrase isozyme XIII with 2-[(1S)-2,3-Dihydro-1H-inden-1-ylamino]-3,5,6-trifluoro-4-[(2-hydroxyethyl)thio]benzenesulfonamide

Summary for 5OHH

• Entry DOI: 10.2210/pdb5ohh/pdb
• Related: 5OGJ
• Descriptor: Carbonic anhydrase 13, 2-[(1S)-2,3-dihydro-1H-inden-1-ylamino]-3,5,6-trifluoro-4-[(2-hydroxyethyl)sulfanyl]benzenesulfonamide, ZINC ION, ... (11 entities in total)
• Functional Keywords: drug design, carbonic anhydrase, benzenesulfonamide, metal-binding, lyase-lyase inhibitor complex, lyase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 61613.85

Authors

Smirnov, A.,Manakova, E.,Grazulis, S. (deposition date: 2017-07-17, release date: 2018-08-08, Last modification date: 2024-01-17)

• Primary citation: Smirnov, A.,Manakova, E.,Grazulis, S.,Matulis, D.; Crystal structure of human carbonic anhydrase isozyme XIII with 2-[(1S)-2,3-Dihydro-1H-inden-1-ylamino]-3,5,6-trifluoro-4-[(2-hydroxyethyl)thio]benzenesulfonamide; To be published,

Experimental method

X-RAY DIFFRACTION (1.42 Å)