Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004089 | molecular_function | carbonate dehydratase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006730 | biological_process | one-carbon metabolic process |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0016829 | molecular_function | lyase activity |
| A | 0043209 | cellular_component | myelin sheath |
| A | 0043231 | cellular_component | intracellular membrane-bounded organelle |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004089 | molecular_function | carbonate dehydratase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006730 | biological_process | one-carbon metabolic process |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0016829 | molecular_function | lyase activity |
| B | 0043209 | cellular_component | myelin sheath |
| B | 0043231 | cellular_component | intracellular membrane-bounded organelle |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue ZN B 301 |
| Chain | Residue |
| B | HIS96 |
| B | HIS98 |
| B | HIS121 |
| B | THR201 |
| B | ACT311 |
| B | HOH423 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue CIT B 302 |
| Chain | Residue |
| B | HIS105 |
| B | SER245 |
| B | HIS247 |
| B | HOH562 |
| B | HOH578 |
| A | HOH463 |
| B | GLY100 |
| B | SER101 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 303 |
| Chain | Residue |
| B | GLN160 |
| B | GLN223 |
| B | LYS227 |
| B | HOH418 |
| B | HOH429 |
| B | HOH431 |
| B | HOH463 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 304 |
| Chain | Residue |
| A | ARG82 |
| A | HOH520 |
| B | PRO189 |
| B | SER190 |
| B | HOH439 |
| B | HOH518 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | binding site for residue AZI B 305 |
| Chain | Residue |
| B | HIS66 |
| B | HIS96 |
| B | HIS98 |
| B | VAL202 |
| B | 5DU313 |
| B | HOH405 |
| B | HOH406 |
| B | HOH423 |
| B | HOH491 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue BCN B 306 |
| Chain | Residue |
| A | TYR42 |
| A | HIS263 |
| B | TYR42 |
| B | ASP43 |
| B | SER44 |
| B | HIS263 |
| B | HOH514 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 307 |
| Chain | Residue |
| A | THR75 |
| A | GLU76 |
| B | ASP103 |
| B | ILE152 |
| B | HOH401 |
| B | HOH420 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 308 |
| Chain | Residue |
| A | THR75 |
| B | SER222 |
| B | GLN223 |
| B | HOH487 |
| B | HOH501 |
| B | HOH503 |
| site_id | AC9 |
| Number of Residues | 10 |
| Details | binding site for residue PEG B 309 |
| Chain | Residue |
| B | LYS36 |
| B | GLU39 |
| B | LEU253 |
| B | LCP310 |
| B | HOH435 |
| B | HOH459 |
| B | HOH472 |
| B | HOH530 |
| B | HOH565 |
| B | HOH700 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue LCP B 310 |
| Chain | Residue |
| B | LYS36 |
| B | GLN223 |
| B | PEG309 |
| B | HOH549 |
| site_id | AD2 |
| Number of Residues | 8 |
| Details | binding site for residue ACT B 311 |
| Chain | Residue |
| B | HIS96 |
| B | HIS121 |
| B | VAL145 |
| B | LEU200 |
| B | THR201 |
| B | ZN301 |
| B | 5DU313 |
| B | HOH423 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue CIT B 312 |
| Chain | Residue |
| B | SER6 |
| B | ARG10 |
| B | GLU11 |
| B | HIS12 |
| B | ASN13 |
| site_id | AD4 |
| Number of Residues | 11 |
| Details | binding site for residue 5DU B 313 |
| Chain | Residue |
| A | LYS257 |
| B | ARG93 |
| B | GLN94 |
| B | HIS96 |
| B | VAL123 |
| B | PHE133 |
| B | VAL202 |
| B | PRO204 |
| B | AZI305 |
| B | ACT311 |
| B | HOH405 |
| site_id | AD5 |
| Number of Residues | 6 |
| Details | binding site for residue ZN A 301 |
| Chain | Residue |
| A | HIS96 |
| A | HIS98 |
| A | HIS121 |
| A | THR201 |
| A | ACT307 |
| A | HOH427 |
| site_id | AD6 |
| Number of Residues | 7 |
| Details | binding site for residue PEG A 302 |
| Chain | Residue |
| A | ASP28 |
| A | GLN29 |
| A | LYS254 |
| A | ARG256 |
| B | LYS59 |
| B | ILE60 |
| B | ARG177 |
| site_id | AD7 |
| Number of Residues | 9 |
| Details | binding site for residue EDO A 303 |
| Chain | Residue |
| A | ILE16 |
| A | LYS19 |
| A | ALA25 |
| A | ASP26 |
| A | GLU154 |
| A | GLN251 |
| A | HOH424 |
| A | HOH494 |
| A | HOH503 |
| site_id | AD8 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 304 |
| Chain | Residue |
| A | ASP43 |
| A | SER45 |
| A | LEU46 |
| A | GLY84 |
| A | ARG259 |
| A | HOH571 |
| A | HOH651 |
| site_id | AD9 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 305 |
| Chain | Residue |
| A | ASP103 |
| A | ASP104 |
| A | ILE152 |
| A | HOH419 |
| A | HOH451 |
| B | GLU76 |
| site_id | AE1 |
| Number of Residues | 9 |
| Details | binding site for residue CIT A 306 |
| Chain | Residue |
| A | GLY100 |
| A | SER101 |
| A | HIS105 |
| A | SER245 |
| A | HIS247 |
| A | HOH518 |
| A | HOH596 |
| A | HOH638 |
| A | HOH658 |
| site_id | AE2 |
| Number of Residues | 7 |
| Details | binding site for residue ACT A 307 |
| Chain | Residue |
| A | HIS96 |
| A | HIS121 |
| A | VAL145 |
| A | LEU200 |
| A | THR201 |
| A | ZN301 |
| A | HOH427 |
| site_id | AE3 |
| Number of Residues | 4 |
| Details | binding site for residue CIT A 308 |
| Chain | Residue |
| A | ARG10 |
| A | GLU11 |
| A | HIS12 |
| A | ASN13 |
Functional Information from PROSITE/UniProt
| site_id | PS00162 |
| Number of Residues | 17 |
| Details | ALPHA_CA_1 Alpha-carbonic anhydrases signature. SEHiVdgvsYaaELHVV |
| Chain | Residue | Details |
| B | SER107-VAL123 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| B | HIS66 | |
| A | HIS66 | |
| Chain | Residue | Details |
| B | HIS96 | |
| B | HIS98 | |
| B | HIS121 | |
| A | HIS96 | |
| A | HIS98 | |
| A | HIS121 | |
| Chain | Residue | Details |
| B | THR201 | |
| A | THR201 | |
