5OF4
The cryo-EM structure of human TFIIH
Summary for 5OF4
Entry DOI | 10.2210/pdb5of4/pdb |
EMDB information | 3802 |
Descriptor | TFIIH basal transcription factor complex helicase XPB subunit,XPB,TFIIH basal transcription factor complex helicase XPB subunit, Unassigned secondary structure elements (XPB NTE region), IRON/SULFUR CLUSTER, ... (11 entities in total) |
Functional Keywords | transcription initiation, dna repair, multiprotein complex, kinase, helicase, transcription |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 10 |
Total formula weight | 306618.26 |
Authors | Greber, B.J.,Nguyen, T.H.D.,Fang, J.,Afonine, P.V.,Adams, P.D.,Nogales, E. (deposition date: 2017-07-10, release date: 2017-09-13, Last modification date: 2024-07-10) |
Primary citation | Greber, B.J.,Nguyen, T.H.D.,Fang, J.,Afonine, P.V.,Adams, P.D.,Nogales, E. The cryo-electron microscopy structure of human transcription factor IIH. Nature, 549:414-417, 2017 Cited by PubMed: 28902838DOI: 10.1038/nature23903 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.4 Å) |
Structure validation
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