5ODT
Aurora-A in complex with TACC3
Summary for 5ODT
Entry DOI | 10.2210/pdb5odt/pdb |
Descriptor | Aurora kinase A, Transforming acidic coiled-coil-containing protein 3, ADENOSINE-5'-DIPHOSPHATE, ... (6 entities in total) |
Functional Keywords | mitotic kinase, transferase |
Biological source | Homo sapiens (Human) More |
Cellular location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome : O14965 Cytoplasm : Q9Y6A5 |
Total number of polymer chains | 2 |
Total formula weight | 39125.17 |
Authors | Burgess, S.G.,Bayliss, R. (deposition date: 2017-07-06, release date: 2018-03-14, Last modification date: 2024-01-17) |
Primary citation | Burgess, S.G.,Mukherjee, M.,Sabir, S.,Joseph, N.,Gutierrez-Caballero, C.,Richards, M.W.,Huguenin-Dezot, N.,Chin, J.W.,Kennedy, E.J.,Pfuhl, M.,Royle, S.J.,Gergely, F.,Bayliss, R. Mitotic spindle association of TACC3 requires Aurora-A-dependent stabilization of a cryptic alpha-helix. EMBO J., 37:-, 2018 Cited by PubMed: 29510984DOI: 10.15252/embj.201797902 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.021 Å) |
Structure validation
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