5OCM

Imine Reductase from Streptosporangium roseum in complex with NADP+ and 2,2,2-trifluoroacetophenone hydrate

Summary for 5OCM

Entry DOI	10.2210/pdb5ocm/pdb
Descriptor	NAD_Gly3P_dh, NAD-dependent glycerol-3-phosphate dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 2,2,2-trifluoromethyl acetophenone hydrate, ... (5 entities in total)
Functional Keywords	imine, amine, nadph, oxidoreductase
Biological source	Streptosporangium roseum
Total number of polymer chains	6
Total formula weight	186027.42
Authors	Sharma, M.,Nestl, B.,Grogan, G. (deposition date: 2017-07-03, release date: 2018-05-16, Last modification date: 2024-01-17)
Primary citation	Lenz, M.,Fademrecht, S.,Sharma, M.,Pleiss, J.,Grogan, G.,Nestl, B.M. New imine-reducing enzymes from beta-hydroxyacid dehydrogenases by single amino acid substitutions. Protein Eng. Des. Sel., 31:109-120, 2018 Cited by PubMed: 29733377 DOI: 10.1093/protein/gzy006 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.81 Å)

Structure validation