5OC7

Crystal structure of the pleckstrin-homology domain of Bcr-Abl in complex with monobody Mb(Bcr-PH_4).

5OC7 の概要

• エントリーDOI: 10.2210/pdb5oc7/pdb
• 分子名称: Breakpoint cluster region protein,pleckstrin-homology domain of Bcr-Abl, monobody Mb(Bcr-PH_4), GLYCEROL, ... (5 entities in total)
• 機能のキーワード: pleckstrin-homology, monobody, bcr-abl, phosphoinositide-binding, signaling protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 51536.44

構造登録者

Reckel, S.,Reynaud, A.,Pojer, F.,Hantschel, O. (登録日: 2017-06-29, 公開日: 2017-12-27, 最終更新日: 2024-01-17)

• 主引用文献: Reckel, S.,Gehin, C.,Tardivon, D.,Georgeon, S.,Kukenshoner, T.,Lohr, F.,Koide, A.,Buchner, L.,Panjkovich, A.,Reynaud, A.,Pinho, S.,Gerig, B.,Svergun, D.,Pojer, F.,Guntert, P.,Dotsch, V.,Koide, S.,Gavin, A.C.,Hantschel, O.; Structural and functional dissection of the DH and PH domains of oncogenic Bcr-Abl tyrosine kinase.; Nat Commun, 8:2101-2101, 2017; PubMed: 29235475; DOI: 10.1038/s41467-017-02313-6

実験手法

X-RAY DIFFRACTION (1.652 Å)