5OAJ

Crystal structure of mutant AChBP in complex with tropisetron (T53F, Q74R, Y110A, I135S, G162E)

Summary for 5OAJ

Entry DOI	10.2210/pdb5oaj/pdb
Descriptor	Soluble acetylcholine receptor, 2-acetamido-2-deoxy-beta-D-glucopyranose, 1,2-ETHANEDIOL, ... (6 entities in total)
Functional Keywords	receptor, acetylcholine binding, signaling protein
Biological source	Aplysia californica (California sea hare)
Total number of polymer chains	10
Total formula weight	288185.42
Authors	Dawson, A.,Hunter, W.N.,de Souza, J.O.,Trumper, P. (deposition date: 2017-06-22, release date: 2018-08-01, Last modification date: 2024-01-17)
Primary citation	Dawson, A.,Trumper, P.,de Souza, J.O.,Parker, H.,Jones, M.J.,Hales, T.G.,Hunter, W.N. Engineering a surrogate human heteromeric alpha / beta glycine receptor orthosteric site exploiting the structural homology and stability of acetylcholine-binding protein. Iucrj, 6:1014-1023, 2019 Cited by PubMed: 31709057 DOI: 10.1107/S205225251901114X PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.47 Å)

Structure validation