5O9M

Crystal structure of human Histamine-Releasing Factor (HRF/TCTP)containing a disulphide-linked dimer

5O9M の概要

• エントリーDOI: 10.2210/pdb5o9m/pdb
• 分子名称: Translationally-controlled tumor protein, DI(HYDROXYETHYL)ETHER (3 entities in total)
• 機能のキーワード: immunoglobulin e, allergy, histamine releasing factor, tctp, hrf, p23, p21, fortilin, immune system
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Cytoplasm : P13693
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 41487.12

構造登録者

Dore, K.A.,Kashiwakura, J.,McDonnell, J.M.,Gould, H.J.,Kawakami, T.,Sutton, B.J.,Davies, A.M. (登録日: 2017-06-19, 公開日: 2017-12-20, 最終更新日: 2024-01-17)

• 主引用文献: Dore, K.A.,Kashiwakura, J.I.,McDonnell, J.M.,Gould, H.J.,Kawakami, T.,Sutton, B.J.,Davies, A.M.; Crystal structures of murine and human Histamine-Releasing Factor (HRF/TCTP) and a model for HRF dimerisation in mast cell activation.; Mol. Immunol., 93:216-222, 2017; PubMed: 29216544; DOI: 10.1016/j.molimm.2017.11.022

実験手法

X-RAY DIFFRACTION (1.4 Å)