5O8Q
Crystal structure of R. ruber ADH-A, mutant Y294F, W295A
Summary for 5O8Q
Entry DOI | 10.2210/pdb5o8q/pdb |
Descriptor | Alcohol dehydrogenase, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... (4 entities in total) |
Functional Keywords | alcohol dehydrogenase mutant variant, nadh-dependent, zn2+-dependent, rossmann fold, oxidoreductase |
Biological source | Rhodococcus sp. M8 |
Total number of polymer chains | 8 |
Total formula weight | 294105.04 |
Authors | Dobritzsch, D.,Maurer, D.,Hamnevik, E.,Enugala, T.R.,Widersten, M. (deposition date: 2017-06-14, release date: 2017-10-11, Last modification date: 2024-01-17) |
Primary citation | Hamnevik, E.,Enugala, T.R.,Maurer, D.,Ntuku, S.,Oliveira, A.,Dobritzsch, D.,Widersten, M. Relaxation of nonproductive binding and increased rate of coenzyme release in an alcohol dehydrogenase increases turnover with a nonpreferred alcohol enantiomer. FEBS J., 284:3895-3914, 2017 Cited by PubMed: 28963762DOI: 10.1111/febs.14279 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.22 Å) |
Structure validation
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