5O6T

BIRC4 RING in complex with dimeric ubiquitin variant

5O6T の概要

分子名称E3 ubiquitin-protein ligase XIAP, Polyubiquitin-B, ZINC ION, ... (5 entities in total)
機能のキーワードe3 ring ligase, ubiquitin variant, ligase
由来する生物種Homo sapiens (Human)
細胞内の位置Cytoplasm P98170
Ubiquitin: Cytoplasm  P0CG47
ポリマー鎖数4
分子量合計33606.43
構造登録者
Gabrielsen, M.,Buetow, L.,Huang, D.T. (登録日: 2017-06-07, 公開日: 2017-11-01)
主引用文献
Gabrielsen, M.,Buetow, L.,Nakasone, M.A.,Ahmed, S.F.,Sibbet, G.J.,Smith, B.O.,Zhang, W.,Sidhu, S.S.,Huang, D.T.
A General Strategy for Discovery of Inhibitors and Activators of RING and U-box E3 Ligases with Ubiquitin Variants.
Mol. Cell, 68:456-470.e10, 2017
PubMed: 29053960 (主引用文献が同じPDBエントリー)
DOI: 10.1016/j.molcel.2017.09.027
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (1.57 Å)
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構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.187100.4%3.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
検証レポート(詳細版)をダウンロード