5O2A

FolD Q98H

Summary for 5O2A

• Entry DOI: 10.2210/pdb5o2a/pdb
• Descriptor: Bifunctional protein FolD, ... (5 entities in total)
• Functional Keywords: carolacton, fold, natural product, inhibitor, oxidoreductase
• Biological source: Escherichia coli (strain K12); More
• Total number of polymer chains: 4
• Total formula weight: 124718.20

Authors

Koehnke, J.,Sikandar, A. (deposition date: 2017-05-19, release date: 2018-02-28, Last modification date: 2024-01-17)

• Primary citation: Fu, C.,Sikandar, A.,Donner, J.,Zaburannyi, N.,Herrmann, J.,Reck, M.,Wagner-Dobler, I.,Koehnke, J.,Muller, R.; The natural product carolacton inhibits folate-dependent C1 metabolism by targeting FolD/MTHFD.; Nat Commun, 8:1529-1529, 2017; PubMed: 29142318; DOI: 10.1038/s41467-017-01671-5

Experimental method

X-RAY DIFFRACTION (1.9 Å)