5NZX

Crystal structure of DNA cross-link repair protein 1A in complex with Ceftriaxone (alternative site)

Summary for 5NZX

Entry DOI	10.2210/pdb5nzx/pdb
Descriptor	DNA cross-link repair 1A protein, NICKEL (II) ION, Ceftriaxone, ... (4 entities in total)
Functional Keywords	exonulcease, cephalosporin, cross-link repair, dclre1a, hydrolase
Biological source	Homo sapiens (Human)
Cellular location	Nucleus : Q6PJP8
Total number of polymer chains	1
Total formula weight	39535.34
Authors	Newman, J.A.,Aitkenhead, H.,Kupinska, K.,Burgess-Brown, N.A.,Talon, R.,Krojer, T.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,Gileadi, O. (deposition date: 2017-05-15, release date: 2017-06-14, Last modification date: 2024-01-17)
Primary citation	Newman, J.A.,Aitkenhead, H.,Kupinska, K.,Burgess-Brown, N.A.,Talon, R.,Krojer, T.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,Gileadi, O. Crystal structure of DNA cross-link repair protein 1A in complex with Ceftriaxone (alternative site) To Be Published,
Experimental method	X-RAY DIFFRACTION (1.47 Å)

Structure validation