5NZK

Crystal structure of UDP-glucose pyrophosphorylase from Leishmania major in complex with phenylalanine

Summary for 5NZK

• Entry DOI: 10.2210/pdb5nzk/pdb
• Related: 2OEF 2OEG 4J18 4M28 4M2A 4M2B
• Descriptor: UDP-glucose pyrophosphorylase, PHENYLALANINE, SULFATE ION, ... (4 entities in total)
• Functional Keywords: ntp-transferase, pathogen, allostery, catalysis, transferase
• Biological source: Leishmania major
• Total number of polymer chains: 1
• Total formula weight: 56316.02

Authors

Cramer, J.T.,Fuehring, J.I.,Baruch, P.,Bruetting, C.,Hesse, R.,Knoelker, H.-J.,Gerardy-Schahn, R.,Fedorov, R. (deposition date: 2017-05-14, release date: 2018-04-18, Last modification date: 2024-01-17)

• Primary citation: Cramer, J.T.,Fuehring, J.I.,Baruch, P.,Bruetting, C.,Knoelker, H.-J.,Gerardy-Schahn, R.,Fedorov, R.; Decoding Allosteric Networks in Biocatalysts: Rational Approach to Therapies and Biotechnologies; Acs Catalysis, 8:-, 2018; DOI: 10.1021/acscatal.7b03714

Experimental method

X-RAY DIFFRACTION (2.45 Å)