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5NZI

Crystal structure of UDP-glucose pyrophosphorylase S374F mutant from Leishmania major in complex with UDP-glucose

Summary for 5NZI
Entry DOI10.2210/pdb5nzi/pdb
Related2OEF 2OEG 4J18 4M28 4M2A 4M2B
DescriptorUDP-glucose pyrophosphorylase, URIDINE-5'-DIPHOSPHATE-GLUCOSE, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywordsntp-transferase, pathogen, allostery, catalysis, transferase
Biological sourceLeishmania major
Total number of polymer chains1
Total formula weight56867.37
Authors
Cramer, J.T.,Fuehring, J.I.,Baruch, P.,Bruetting, C.,Hesse, R.,Knoelker, H.-J.,Gerardy-Schahn, R.,Fedorov, R. (deposition date: 2017-05-14, release date: 2018-04-18, Last modification date: 2024-01-17)
Primary citationCramer, J.T.,Fuehring, J.I.,Baruch, P.,Bruetting, C.,Knoelker, H.-J.,Gerardy-Schahn, R.,Fedorov, R.
Decoding Allosteric Networks in Biocatalysts: Rational Approach to Therapies and Biotechnologies
Acs Catalysis, 8:-, 2018
Cited by
DOI: 10.1021/acscatal.7b03714
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.05 Å)
Structure validation

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