5NZI
Crystal structure of UDP-glucose pyrophosphorylase S374F mutant from Leishmania major in complex with UDP-glucose
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003983 | molecular_function | UTP:glucose-1-phosphate uridylyltransferase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0005977 | biological_process | glycogen metabolic process |
| A | 0006011 | biological_process | UDP-alpha-D-glucose metabolic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| A | 0031981 | cellular_component | nuclear lumen |
| A | 0070569 | molecular_function | uridylyltransferase activity |
| A | 0097014 | cellular_component | ciliary plasm |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 23 |
| Details | binding site for residue UPG A 601 |
| Chain | Residue |
| A | LEU81 |
| A | GLY256 |
| A | GLY257 |
| A | GLU284 |
| A | PHE305 |
| A | ASN306 |
| A | ASN308 |
| A | PHE376 |
| A | LYS380 |
| A | HOH765 |
| A | HOH774 |
| A | GLY83 |
| A | HOH799 |
| A | HOH801 |
| A | HOH805 |
| A | HOH811 |
| A | GLY84 |
| A | MET130 |
| A | GLN162 |
| A | GLY190 |
| A | HIS191 |
| A | ASN219 |
| A | GLY220 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 602 |
| Chain | Residue |
| A | GLN210 |
| A | TYR212 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 604 |
| Chain | Residue |
| A | GLU67 |
| A | LYS229 |
