5NX9
Crystal structure of Neanderthal Adenylosuccinate Lyase (ADSL) in complex with its products AMP and fumarate
Summary for 5NX9
Entry DOI | 10.2210/pdb5nx9/pdb |
Descriptor | Adenylosuccinate lyase, CHLORIDE ION, ADENOSINE MONOPHOSPHATE, ... (8 entities in total) |
Functional Keywords | adenylosuccinate lyase, fumarase, lyase |
Biological source | Homo sapiens neanderthalensis |
Total number of polymer chains | 4 |
Total formula weight | 224403.32 |
Authors | Van Laer, B.,Kapp, U.,Soler-Lopez, M.,Leonard, G.,Mueller-Dieckmann, C. (deposition date: 2017-05-09, release date: 2018-05-30, Last modification date: 2024-01-17) |
Primary citation | Van Laer, B.,Kapp, U.,Soler-Lopez, M.,Moczulska, K.,Paabo, S.,Leonard, G.,Mueller-Dieckmann, C. Molecular comparison of Neanderthal and Modern Human adenylosuccinate lyase. Sci Rep, 8:18008-18008, 2018 Cited by PubMed: 30573755DOI: 10.1038/s41598-018-36195-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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