5NX9
Crystal structure of Neanderthal Adenylosuccinate Lyase (ADSL) in complex with its products AMP and fumarate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Adenylosuccinate lyase | polymer | 487 | 55216.4 | 4 | Pfam (PF00206) Pfam (PF10397) UniProt (by SIFTS) (A0A384E0N4) | Homo sapiens neanderthalensis | |
| 2 | E, F, N, R, S... (A, B, C, D) | CHLORIDE ION | non-polymer | 35.5 | 6 | Chemie (CL) | |||
| 3 | G, Z (A, D) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 2 | Chemie (AMP) | |||
| 4 | AA, H (D, A) | FUMARIC ACID | non-polymer | 116.1 | 2 | Chemie (FUM) | |||
| 5 | BA, CA, DA, I, J... (D, A, B, C) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 13 | Chemie (PEG) | |||
| 6 | O, Q (B, C) | 2-[9-(3,4-DIHYDROXY-5-PHOSPHONOOXYMETHYL-TETRAHYDRO-FURAN-2-YL)-9H-PURIN-6-YLAMINO]-SUCCINIC ACID | non-polymer | 463.3 | 2 | Chemie (2SA) | |||
| 7 | W (C) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 8 | EA, FA, GA, HA (A, B, C, D) | water | water | 18.0 | 397 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 220865.8 | |
| Non-Polymers* | Number of molecules | 26 |
| Total formula weight | 3537.5 | |
| All* | Total formula weight | 224403.3 |
