5NW7

Crystal structure of candida albicans phosphomannose isomerase in complex with inhibitor

Summary for 5NW7

Entry DOI	10.2210/pdb5nw7/pdb
Descriptor	Mannose-6-phosphate isomerase, ZINC ION, [(2~{R},3~{R},4~{S})-5-diazanyl-2,3,4-tris(oxidanyl)-5-oxidanylidene-pentyl] dihydrogen phosphate, ... (4 entities in total)
Functional Keywords	aldose-ketose isomerase, isomerase, complex inhibitor
Biological source	Candida albicans (Yeast)
Total number of polymer chains	1
Total formula weight	50854.71
Authors	Li de la Sierra-Gallay, I.,Ahmad, L.,Plancqueel, S.,van Tilbeurgh, H.,Salmon, L. (deposition date: 2017-05-05, release date: 2018-05-02, Last modification date: 2024-01-17)
Primary citation	Ahmad, L.,Plancqueel, S.,Dubosclard, V.,Lazar, N.,Ghattas, W.,Li de la Sierra-Gallay, I.,van Tilbeurgh, H.,Salmon, L. Crystal structure of phosphomannose isomerase from Candida albicans complexed with 5-phospho-d-arabinonhydrazide. FEBS Lett., 592:1667-1680, 2018 Cited by PubMed: 29687459 DOI: 10.1002/1873-3468.13059 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation