5NW7
Crystal structure of candida albicans phosphomannose isomerase in complex with inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Mannose-6-phosphate isomerase | polymer | 455 | 50529.2 | 1 | UniProt (P34948) Pfam (PF20511) Pfam (PF20512) Pfam (PF01238) In PDB | Candida albicans (Yeast) | Phosphohexomutase,Phosphomannose isomerase,PMI |
2 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
3 | A | [(2~{R},3~{R},4~{S})-5-diazanyl-2,3,4-tris(oxidanyl)-5-oxidanylidene-pentyl] dihydrogen phosphate | non-polymer | 260.1 | 1 | Chemie (9C2) | |||
4 | water | water | 18.0 | 247 | Chemie (HOH) |
Sequence modifications
A: 1 - 441 (UniProt: P34948)
PDB | External Database | Details |
---|---|---|
Met -13 | - | initiating methionine |
Arg -12 | - | expression tag |
Gly -11 | - | expression tag |
Ser -10 | - | expression tag |
His -9 | - | expression tag |
His -8 | - | expression tag |
His -7 | - | expression tag |
His -6 | - | expression tag |
His -5 | - | expression tag |
His -4 | - | expression tag |
Gly -3 | - | expression tag |
Met -2 | - | expression tag |
Ala -1 | - | expression tag |
Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 50529.2 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 325.5 | |
All* | Total formula weight | 50854.7 |