5NW7

Crystal structure of candida albicans phosphomannose isomerase in complex with inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Mannose-6-phosphate isomerase	polymer	455	50529.2	1	UniProt (P34948) Pfam (PF20511) Pfam (PF20512) Pfam (PF01238)	Candida albicans (Yeast)	Phosphohexomutase,Phosphomannose isomerase,PMI
2	B (A)	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
3	C (A)	[(2~{R},3~{R},4~{S})-5-diazanyl-2,3,4-tris(oxidanyl)-5-oxidanylidene-pentyl] dihydrogen phosphate	non-polymer		260.1	1	Chemie (9C2)
4	D (A)	water	water		18.0	247	Chemie (HOH)

Sequence modifications

A: 1 - 441 (UniProt: P34948)

PDB	External Database	Details
Met -13	-	initiating methionine
Arg -12	-	expression tag
Gly -11	-	expression tag
Ser -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
Gly -3	-	expression tag
Met -2	-	expression tag
Ala -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	50529.2
Non-Polymers*	Number of molecules	2
	Total formula weight	325.5
All*	Total formula weight	50854.7

*Water molecules are not included.