5NVM
Crystal structure of the human 4EHP-GIGYF2 complex lacking the auxiliary sequences
Summary for 5NVM
Entry DOI | 10.2210/pdb5nvm/pdb |
Descriptor | Eukaryotic translation initiation factor 4E type 2, GRB10-interacting GYF protein 2, PHOSPHATE ION, ... (4 entities in total) |
Functional Keywords | translational regulation, cap-binding protein, 4ehp-binding protein, grb10-interacting gyf protein 2, translation |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 54375.87 |
Authors | Peter, D.,Valkov, E. (deposition date: 2017-05-04, release date: 2017-07-26, Last modification date: 2024-01-17) |
Primary citation | Peter, D.,Weber, R.,Sandmeir, F.,Wohlbold, L.,Helms, S.,Bawankar, P.,Valkov, E.,Igreja, C.,Izaurralde, E. GIGYF1/2 proteins use auxiliary sequences to selectively bind to 4EHP and repress target mRNA expression. Genes Dev., 31:1147-1161, 2017 Cited by PubMed: 28698298DOI: 10.1101/gad.299420.117 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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