5NVK

Crystal structure of the human 4EHP-GIGYF1 complex

Summary for 5NVK

• Entry DOI: 10.2210/pdb5nvk/pdb
• Descriptor: Eukaryotic translation initiation factor 4E type 2, GRB10-interacting GYF protein 1 (2 entities in total)
• Functional Keywords: translational regulation, cap-binding protein, 4ehp-binding protein, grb10-interacting gyf protein 1, translation
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 8
• Total formula weight: 122848.26

Authors

Peter, D.,Valkov, E. (deposition date: 2017-05-04, release date: 2017-07-26, Last modification date: 2024-01-17)

• Primary citation: Peter, D.,Weber, R.,Sandmeir, F.,Wohlbold, L.,Helms, S.,Bawankar, P.,Valkov, E.,Igreja, C.,Izaurralde, E.; GIGYF1/2 proteins use auxiliary sequences to selectively bind to 4EHP and repress target mRNA expression.; Genes Dev., 31:1147-1161, 2017; PubMed: 28698298; DOI: 10.1101/gad.299420.117

Experimental method

X-RAY DIFFRACTION (2.9 Å)