5NTN
Structural states of RORgt: X-ray elucidation of molecular mechanisms and binding interactions for natural and synthetic compounds
Summary for 5NTN
Entry DOI | 10.2210/pdb5ntn/pdb |
Descriptor | Nuclear receptor ROR-gamma, Nuclear receptor-interacting protein 1, (5R,10S,13R,14R,17R)-17-((R,E)-7-hydroxy-6-methylhept-5-en-2-yl)-4,4,10,13,14-pentamethyl-1,2,5,6,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-3,7(4H)-dione, ... (4 entities in total) |
Functional Keywords | nuclear hormone receptor, ligand-binding domain, agonist, signaling protein |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus : P51449 P48552 |
Total number of polymer chains | 8 |
Total formula weight | 130054.46 |
Authors | Kallen, J. (deposition date: 2017-04-28, release date: 2017-06-21, Last modification date: 2024-01-17) |
Primary citation | Kallen, J.,Izaac, A.,Be, C.,Arista, L.,Orain, D.,Kaupmann, K.,Guntermann, C.,Hoegenauer, K.,Hintermann, S. Structural States of ROR gamma t: X-ray Elucidation of Molecular Mechanisms and Binding Interactions for Natural and Synthetic Compounds. ChemMedChem, 12:1014-1021, 2017 Cited by PubMed: 28590087DOI: 10.1002/cmdc.201700278 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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