5NTI

Structural states of RORgt: X-ray elucidation of molecular mechanisms and binding interactions for natural and synthetic compounds

5NTI の概要

• エントリーDOI: 10.2210/pdb5nti/pdb
• 分子名称: Nuclear receptor ROR-gamma, ASN-SER-HIS-GLN-LYS-VAL-THR-LEU-LEU-GLN-LEU-LEU-LEU-GLY-HIS-LYS-ASN-GLU-GLU-ASN, CHOLEST-5-EN-3-YL HYDROGEN SULFATE, ... (4 entities in total)
• 機能のキーワード: nuclear hormone receptor, ligand-binding domain, agonist, signaling protein
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Nucleus : P51449
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 130102.59

構造登録者

Kallen, J. (登録日: 2017-04-28, 公開日: 2017-06-21, 最終更新日: 2024-05-01)

• 主引用文献: Kallen, J.,Izaac, A.,Be, C.,Arista, L.,Orain, D.,Kaupmann, K.,Guntermann, C.,Hoegenauer, K.,Hintermann, S.; Structural States of ROR gamma t: X-ray Elucidation of Molecular Mechanisms and Binding Interactions for Natural and Synthetic Compounds.; ChemMedChem, 12:1014-1021, 2017; PubMed: 28590087; DOI: 10.1002/cmdc.201700278

実験手法

X-RAY DIFFRACTION (2.4 Å)