5NRQ

Mtb TMK crystal structure in complex with compound 33

Summary for 5NRQ

• Entry DOI: 10.2210/pdb5nrq/pdb
• Descriptor: Thymidylate kinase, 1-[1-[[5-(3-chloranylphenoxy)pyridin-3-yl]methyl]piperidin-4-yl]-5-methyl-pyrimidine-2,4-dione, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: thymidylate kinase, nucleotide binding, inhibitor, transferase
• Biological source: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
• Total number of polymer chains: 2
• Total formula weight: 46320.65

Authors

Merceron, R.,Song, L.,Munier-Lehmann, H.,Van Calenbergh, S.,Savvides, S. (deposition date: 2017-04-25, release date: 2018-08-08, Last modification date: 2024-01-17)

• Primary citation: Merceron, R.,Song, L.,Munier-Lehmann, H.,Van Calenbergh, S.,Savvides, S.; Mtb TMK crystal structure in complex with compound LS3112; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.1 Å)