5NRB

A Native Ternary Complex of Alpha-1,3-Galactosyltransferase (a-3GalT) Supports a Conserved Reaction Mechanism for Retaining Glycosyltransferases - alpha-3GalT in complex with Co2+, UDP-Gal and lactose - a3GalT-Co2+-UDP-Gal-LAT-1

Summary for 5NRB

Entry DOI	10.2210/pdb5nrb/pdb
Related PRD ID	PRD_900004
Descriptor	N-acetyllactosaminide alpha-1,3-galactosyltransferase, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, COBALT (II) ION, ... (5 entities in total)
Functional Keywords	glycosyltransferase, gta, transferase
Biological source	Bos taurus (Bovine)
Cellular location	Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein: P14769
Total number of polymer chains	2
Total formula weight	70323.75
Authors	Albesa-Jove, D.,Marina, A.,Sainz-Polo, M.A.,Guerin, M.E. (deposition date: 2017-04-22, release date: 2017-10-11, Last modification date: 2024-01-17)
Primary citation	Albesa-Jove, D.,Sainz-Polo, M.A.,Marina, A.,Guerin, M.E. Structural Snapshots of alpha-1,3-Galactosyltransferase with Native Substrates: Insight into the Catalytic Mechanism of Retaining Glycosyltransferases. Angew. Chem. Int. Ed. Engl., 56:14853-14857, 2017 Cited by PubMed: 28960760 DOI: 10.1002/anie.201707922 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.24 Å)

Structure validation