5NPQ

Human N-myristoyltransferase 1 (MNT1) with Myristoyl-CoA analogue X10 bound

Summary for 5NPQ

• Entry DOI: 10.2210/pdb5npq/pdb
• Related: 4C2Y 4C2Z 5MU6
• Descriptor: Glycylpeptide N-tetradecanoyltransferase 1, GLYCEROL, ~{S}-[2-[3-[[(2~{S})-4-[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyl] 9-(3-but-3-ynyl-1,2-diazirin-3-yl)nonanethioate, ... (5 entities in total)
• Functional Keywords: n-myristoylation, transferase, myristol-coa analogue, uv active, chemical probe
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 93323.39

Authors

Shen, M.,Perez-Dorado, I.,Fedoryshchak, R.,Tate, E.W. (deposition date: 2017-04-18, release date: 2018-05-30, Last modification date: 2024-01-17)

• Primary citation: Shen, M.,Perez-Dorado, I.,Fedoryshchak, R.,Tate, E.W.; Human N-myristoyltransferase 1 (MNT1) with Myristoyl-CoA analogue X10 bound.; To be published,

Experimental method

X-RAY DIFFRACTION (2.372 Å)