5NPQ
Human N-myristoyltransferase 1 (MNT1) with Myristoyl-CoA analogue X10 bound
Summary for 5NPQ
Entry DOI | 10.2210/pdb5npq/pdb |
Related | 4C2Y 4C2Z 5MU6 |
Descriptor | Glycylpeptide N-tetradecanoyltransferase 1, GLYCEROL, ~{S}-[2-[3-[[(2~{S})-4-[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyl] 9-(3-but-3-ynyl-1,2-diazirin-3-yl)nonanethioate, ... (5 entities in total) |
Functional Keywords | n-myristoylation, transferase, myristol-coa analogue, uv active, chemical probe |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 93323.39 |
Authors | Shen, M.,Perez-Dorado, I.,Fedoryshchak, R.,Tate, E.W. (deposition date: 2017-04-18, release date: 2018-05-30, Last modification date: 2024-01-17) |
Primary citation | Shen, M.,Perez-Dorado, I.,Fedoryshchak, R.,Tate, E.W. Human N-myristoyltransferase 1 (MNT1) with Myristoyl-CoA analogue X10 bound. To be published, |
Experimental method | X-RAY DIFFRACTION (2.372 Å) |
Structure validation
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