5NNO

Structure of TbALDH3 complexed with NAD and AN3057 aldehyde

Summary for 5NNO

Entry DOI	10.2210/pdb5nno/pdb
Related	5MYP
Descriptor	Aldehyde dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 4-[(1-oxidanyl-3~{H}-2,1-benzoxaborol-5-yl)oxy]benzaldehyde, ... (4 entities in total)
Functional Keywords	aldehyde dehydrogenase, aldh, trypanosoma brucei, glycosomal, oxidoreductase, oxaborole, nad
Biological source	Trypanosoma brucei
Total number of polymer chains	2
Total formula weight	121760.89
Authors	Zoltner, M.,Zhang, N.,Horn, D.,Field, M.C. (deposition date: 2017-04-10, release date: 2017-04-19, Last modification date: 2024-01-17)
Primary citation	Zhang, N.,Zoltner, M.,Leung, K.F.,Scullion, P.,Hutchinson, S.,Del Pino, R.C.,Vincent, I.M.,Zhang, Y.K.,Freund, Y.R.,Alley, M.R.K.,Jacobs, R.T.,Read, K.D.,Barrett, M.P.,Horn, D.,Field, M.C. Host-parasite co-metabolic activation of antitrypanosomal aminomethyl-benzoxaboroles. PLoS Pathog., 14:e1006850-e1006850, 2018 Cited by PubMed: 29425238 DOI: 10.1371/journal.ppat.1006850 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation