5NN1

The structure of the polo-box domain (PBD) of polo-like kinase 1 (Plk1)

Summary for 5NN1

• Entry DOI: 10.2210/pdb5nn1/pdb
• Descriptor: Serine/threonine-protein kinase PLK1 (2 entities in total)
• Functional Keywords: plk1, pbd1, mitosis, transferase
• Biological source: Homo sapiens (Human)
• Cellular location: Nucleus: P53350
• Total number of polymer chains: 1
• Total formula weight: 27285.16

Authors

Kunciw, D.L.,Rossmann, M.,De Fusco, C.,Spring, D.R.,Hyvonen, M. (deposition date: 2017-04-07, release date: 2018-02-21, Last modification date: 2024-06-19)

• Primary citation: Kunciw, D.L.,De Fusco, C.,Rossmann, M.,De Andres, M.,Sore, H.F.,Hyvonen, M.,Spring, D.R.; Developing peptidic inhibitors of the cryptic pocket of the Polo-Like Kinase 1 Polo-Box Domain.; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.785 Å)