5NLF

Crystal structure of Zn2.7-E16V human ubiquitin (hUb) mutant adduct, from a solution 100 mM zinc acetate/1.3 mM E16V hUb

Summary for 5NLF

• Entry DOI: 10.2210/pdb5nlf/pdb
• Related: 3EHV 4K7W 4KTS 4KTU
• Descriptor: Polyubiquitin-C, ZINC ION, ACETATE ION, ... (4 entities in total)
• Functional Keywords: e16v mutant, ligase, ubiquitination, proteasome degradation, immune system
• Biological source: Homo sapiens (Human)
• Cellular location: Ubiquitin: Cytoplasm : P0CG48
• Total number of polymer chains: 3
• Total formula weight: 26589.85

Authors

Fermani, S.,Falini, G. (deposition date: 2017-04-04, release date: 2017-05-03, Last modification date: 2024-01-17)

• Primary citation: Fermani, S.,Calvaresi, M.,Mangini, V.,Falini, G.,Bottoni, A.,Natile, G.,Arnesano, F.; Aggregation Pathways of Native-Like Ubiquitin Promoted by Single-Point Mutation, Metal Ion Concentration, and Dielectric Constant of the Medium.; Chemistry, 24:4140-4148, 2018; PubMed: 29266436; DOI: 10.1002/chem.201705543

Experimental method

X-RAY DIFFRACTION (1.5 Å)