5NG0
Structure of RIP2K(L294F) with bound AMPPCP
Summary for 5NG0
Entry DOI | 10.2210/pdb5ng0/pdb |
Descriptor | Receptor-interacting serine/threonine-protein kinase 2, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | rip2k, kinase, active state, amppcpp, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 70809.90 |
Authors | Pellegrini, E.,Cusack, S. (deposition date: 2017-03-16, release date: 2017-06-07, Last modification date: 2024-01-17) |
Primary citation | Pellegrini, E.,Signor, L.,Singh, S.,Boeri Erba, E.,Cusack, S. Structures of the inactive and active states of RIP2 kinase inform on the mechanism of activation. PLoS ONE, 12:e0177161-e0177161, 2017 Cited by PubMed: 28545134DOI: 10.1371/journal.pone.0177161 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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