5NFO
Human JMJD7 in complex with Mn and 2OG in the P21212 form
5NFO の概要
エントリーDOI | 10.2210/pdb5nfo/pdb |
関連するPDBエントリー | 5nfn |
分子名称 | JmjC domain-containing protein 7, MANGANESE (II) ION, 2-OXOGLUTARIC ACID, ... (6 entities in total) |
機能のキーワード | oxidoreductase, non-heme, iron, 2-oxoglutarate, dioxygenase, oxygenase, jmjc, jmjc domain, jmjc domain-containing protein 7, jmjd7, jmjc hydroxylase, jmjc demethylase, kdms, post-translational modifications, ptm, hydroxylation, lysyl hydroxylation, dimerisation, translation factor, developmentally regulated gtp binding proteins, drg1, drg2, trafac gtpase, hypoxia, nucleic acid-binding, metal-binding, translation, helix-loop-helix-beta, dsbh, facial triad, development, cancer, ribosome biogenesis |
由来する生物種 | Homo sapiens (Human) |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 76986.79 |
構造登録者 | |
主引用文献 | Markolovic, S.,Zhuang, Q.,Wilkins, S.E.,Eaton, C.,Katz, M.J.,Smith, H.E.,Lesniak, R.K.,Hall, C.,Struwe, W.B.,Konietzny, R.,Davis, S.,Yang, M.,Ge, W.,Benesch, J.L.,Kessler, B.M.,Ratcliffe, P.J.,Cockman, M.E.,Fischer, R.,Wappner, P.,Chowdhury, R.,Coleman, M.L.,Schofield, C.J. (3S)-Lysyl hydroxylation of TRAFAC GTPases is catalyzed by the human Jumonji-C oxygenase JMJD7. To Be Published, |
実験手法 | X-RAY DIFFRACTION (2.173 Å) |
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