5NFO

Human JMJD7 in complex with Mn and 2OG in the P21212 form

5NFO の概要

• エントリーDOI: 10.2210/pdb5nfo/pdb
• 関連するPDBエントリー: 5nfn
• 分子名称: JmjC domain-containing protein 7, MANGANESE (II) ION, 2-OXOGLUTARIC ACID, ... (6 entities in total)
• 機能のキーワード: oxidoreductase, non-heme, iron, 2-oxoglutarate, dioxygenase, oxygenase, jmjc, jmjc domain, jmjc domain-containing protein 7, jmjd7, jmjc hydroxylase, jmjc demethylase, kdms, post-translational modifications, ptm, hydroxylation, lysyl hydroxylation, dimerisation, translation factor, developmentally regulated gtp binding proteins, drg1, drg2, trafac gtpase, hypoxia, nucleic acid-binding, metal-binding, translation, helix-loop-helix-beta, dsbh, facial triad, development, cancer, ribosome biogenesis
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 76986.79

構造登録者

Chowdhury, R.,Markolovic, S.,Schofield, C.J. (登録日: 2017-03-14, 公開日: 2018-03-14, 最終更新日: 2024-01-17)

• 主引用文献: Markolovic, S.,Zhuang, Q.,Wilkins, S.E.,Eaton, C.,Katz, M.J.,Smith, H.E.,Lesniak, R.K.,Hall, C.,Struwe, W.B.,Konietzny, R.,Davis, S.,Yang, M.,Ge, W.,Benesch, J.L.,Kessler, B.M.,Ratcliffe, P.J.,Cockman, M.E.,Fischer, R.,Wappner, P.,Chowdhury, R.,Coleman, M.L.,Schofield, C.J.; (3S)-Lysyl hydroxylation of TRAFAC GTPases is catalyzed by the human Jumonji-C oxygenase JMJD7.; To Be Published,

実験手法

X-RAY DIFFRACTION (2.173 Å)