5NFO

Human JMJD7 in complex with Mn and 2OG in the P21212 form

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	JmjC domain-containing protein 7	polymer	335	37954.1	2	UniProt (P0C870) Pfam (PF13621) In PDB	Homo sapiens (Human)	Jumonji domain-containing protein 7
2	A, B	MANGANESE (II) ION	non-polymer		54.9	2	Chemie (MN)
3	A, B	2-OXOGLUTARIC ACID	non-polymer		146.1	2	Chemie (AKG)
4	A, B	GLYCEROL	non-polymer		92.1	6	Chemie (GOL)
5	A, B	NITRATE ION	non-polymer		62.0	2	Chemie (NO3)
6		water	water		18.0	308	Chemie (HOH)

Sequence modifications

A, B: 1 - 316 (UniProt: P0C870)

PDB	External Database	Details
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
Cys 260	Arg 260	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	75908.1
Non-Polymers*	Number of molecules	12
	Total formula weight	1078.6
All*	Total formula weight	76986.8

*Water molecules are not included.