5NEB
Structure of GluK1 ligand-binding domain (S1S2) in complex with LM-12b at 2.05 A resolution
Summary for 5NEB
Entry DOI | 10.2210/pdb5neb/pdb |
Descriptor | Glutamate receptor ionotropic, kainate 1, SULFATE ION, CHLORIDE ION, ... (7 entities in total) |
Functional Keywords | ionotropic glutamate receptor, kainate receptor, ligand-binding domain, gluk1, glur5, agonist, membrane protein |
Biological source | Rattus norvegicus (Rat) More |
Cellular location | Cell membrane; Multi-pass membrane protein: P22756 |
Total number of polymer chains | 2 |
Total formula weight | 59796.84 |
Authors | Moellerud, S.,Frydenvang, K.,Laulumaa, S.,Kastrup, J.S. (deposition date: 2017-03-10, release date: 2017-07-26, Last modification date: 2024-01-17) |
Primary citation | Mllerud, S.,Pinto, A.,Marconi, L.,Frydenvang, K.,Thorsen, T.S.,Laulumaa, S.,Venskutonyte, R.,Winther, S.,Moral, A.M.C.,Tamborini, L.,Conti, P.,Pickering, D.S.,Kastrup, J.S. Structure and Affinity of Two Bicyclic Glutamate Analogues at AMPA and Kainate Receptors. ACS Chem Neurosci, 8:2056-2064, 2017 Cited by PubMed: 28691798DOI: 10.1021/acschemneuro.7b00201 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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